Effect of alpha-methyldopa excreted in human milk on the breast-fed infant
Hauser, G.J.; Almog, S.; Tirosh, M.; Spirer, Z.
Helvetica Paediatrica Acta 40(1): 83-86
1985
ISSN/ISBN: 0018-022X PMID: 3843238 Document Number: 261166
A nursing infant whose mother took alpha-methyldopa (alpha-MD) was followed for 3 months. Analysis of maternal serum and milk as well as the infant's serum and urine for alpha-MD revealed that the drug was excreted into maternal milk, absorbed by the infant and excreted in her urine, but no adverse clinical effects were noted during the follow-up period. alpha-MD is excreted in human milk in concentrations that probably do not harm the breast-fed infant.
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