The functional characteristics of the reproductive system in women who are heterozygous carriers of 21-hydroxylase deficiency
Dzenis, I.G.; Brykova, E.K.; Bakharev, V.A.; Fanchenko, N.D.; Semenova, N.V.
Akusherstvo i Ginekologiia 9: 49-51
1990
ISSN/ISBN: 0300-9092 PMID: 2177586 Document Number: 359798
This paper reports the results of evaluation of reproductive histories of 52 heterozygous female carriers of 21-hydroxylase deficiency who gave birth to children with classic congenital adrenocortical hyperplasia. Functional ACTH adrenal tests of these women were compared with those in a control group of noncarriers. Test findings are discussed with respect to the pathogenesis of reproductive tract disorders in the carriers of a mutant gene.