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Individual features of sex-related resistance of animals to hypoxia

Korneev, A.A.

Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 5: 31-33

1990

ISSN/ISBN: 0031-2991
PMID: 2293160
Document Number: 359548
Comparative evaluation of sex-related resistance of rats to hypoxia was undertaken. Acute hypoxic hypoxia modelled in a plenum-exhaust pressure chamber was tolerated by female rats better than by male animals. The disorders of energy metabolism and contractile function of an isolated contracting heart caused by acute hypoxia are manifested much earlier and are more severe in males than in females. Thus the organism of females in much more resistant to acute hypoxic hypoxia than the organism of males, i.e., there is a correlation between the individual sensitivity of the organism to hypoxia and its sex.

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