Comparison of the effects of organic dusts on respiratory organs of rats using a morphometric method
Tacheva, I.; Dlukhosh, M.; Dolezhel, S.; Shimchikova, B.; Vashku, I.
Gigiena Truda i Professional'nye Zabolevaniya (6): 10-12
1990
ISSN/ISBN: 0016-9919 PMID: 2394395 Document Number: 357495
The contributors studied changes in the respiratory organs in rats induced by lucerne, maize, cotton, flax and flour dusts. The dusts were administered intratracheally by 10 mg dosages. Histological studies of the lung parenchyma were performed in 3 months, which revealed granuloma formations caused by the dusts. Automized planimetry was used to measure the surfaces, both individual and total, of the granuloma formations. To this criterion, cotton dust proved most affective (2.423 +/- 0.772), followed by lucerne (1.739 +/- 0.694), maize (1.434 +/- 0.558), flax (1.420 +/- 0.329), and flour (0.565 +/- 0.171) dusts.