ICO-10 (Thy-1) and K-20 (gp 120/200) monoclonal antibodies in immunophenotyping of solid tumors in man
Kadagidze, Z.G.; Tupitsyn, N.N.; Kadyrov, K.P.; Baryshnikov, A.I.; Mentkevich, G.L.; Matiakin, G.G.; Blinov, V.M.
Voprosy Onkologii 36(3): 296-303
1990
ISSN/ISBN: 0507-3758 PMID: 2330681 Document Number: 357299
ICO - 10 (Thy-1 antigen) and K 20 (gp 120/200) monoclonal antibodies proved suitable for immunophenotyping solid tumors. The following typical antigen combinations were identified with regard to reaction with those antibodies: ICO - 10+ K 20- (neuroblastoma, malignant schwannoma, neurosarcoma and soft tissue sarcomas); K 20+ ICO - 10- (cancer of the tongue and esophagus, adenoma of the adrenal cortex, adenocarcinoma of the stomach, hepatoblastoma and nephroblastoma); ICO - 10+ K 20+ (immature teratoma and cervical and esophageal leiomyoma) and ICO - 10+ K 20- (malignant fibrous histiocytoma).