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The effect of fibronectin preparations on the chemiluminescence of neutrophils

Zinkevich, O.D.; Safina, N.A.; Kharrasov, A.F.; Mingazova, A.K.

Voprosy Meditsinskoi Khimii 36(2): 53-55

1990

ISSN/ISBN: 0042-8809
PMID: 2363260
Document Number: 357272
Effect of some fibronectin preparations on luminol-dependent chemiluminescence of neutrophils was studied. These fibronectin preparations were obtained after heat denaturation and tryptic digestion. Native fibronectin cause aggregation of gelatin-coated particles and dose-dependent promotion of chemiluminescence of neutrophils, while the rate of these reactions was distinctly decreased if the heat denaturated preparations of fibronectin were used. Structural integrity of fibronectin molecule appears to be responsible for promotion of the neutrophil chemiluminescence.

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