The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydro-homopyrimidazol-methylsulphate (MZ-144) , a new, potent, non narcotic analgesic. I. Some basic correlations between the chemical structure and activity of homopyrimidazol analgesics. Selection of MZ-144
Knoll, J.; Mészáros, Z.; Szentmiklósi, P.; Fürst, S.
Arzneimittel-Forschung 21(5): 717-719
1971
ISSN/ISBN: 0004-4172 PMID: 5109700 Document Number: 35721
Document emailed within 1 workday
Related Documents
Knoll, J.; Magyar, K.; Bánfi, D. 1971: The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydro-homopyrimidazol-methylsulphate (MZ-144), a new, potent, non-narcotic analgesic. IV. the fate of MZ-144 within the organism Arzneimittel-Forschung 21(5): 733-738Knoll, J.; Fürst, S.; Mészáros, Z. 1971: The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydro-homopyrimidazol-methylsulphate (MZ-144), a new, potent, non-narcotic analgesic. 3. Analysis of the central and peripheric effects Arzneimittel-Forschung 21(5): 727-733
Magyar, K.; Knoll, J. 1973: Distribution of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydrohomopyrimidazole-methylsulphate (MZ-144, Probon) Acta Physiologica Academiae Scientiarum Hungaricae 43(4): 353-358
Huang, Z.M.; Zhou, J.; Chen, X.J.; Zheng, W.J.; Zhang, H.P.; Chi, Z.Q.; Li, Z.G.; Chen, W.L. 1984: Analgesic activity and toxicity of potent analgesics, ohmefentanyl and mefentanyl Zhongguo Yao Li Xue Bao 5(3): 153-158
Colpaert, F.C.; Niemegeers, C.J.; Janssen, P.A. 1976: Discriminative stimulus properties of analgesic drugs: narcotic versus non-narcotic analgesics Archives Internationales de Pharmacodynamie et de Therapie 220(2): 329-332
Malec, D.; Grabowska, E.; Langwiński, R. 1978: Central action of narcotic analgesics. Part IV. Noradrenergic influences on the activity of analgesics in rats Polish Journal of Pharmacology and Pharmacy 30(5): 627-637
Malec, D.; Fidecka, S.; Langwiński, R. 1977: Central action of narcotic analgesics. I. Catalepsy and stereotypy in rats and narcotic analgesics Polish Journal of Pharmacology and Pharmacy 29(3): 177-193
Stets, V.R.; Slivko, S.F. 1988: Effect of adrenoblocking agents and melipramine on the analgesic effect of non-narcotic analgesics Anesteziologiia i Reanimatologiia 1: 54-57
Sasaki, T.; Abiko, N.; Uchida, H.; Tanaka, M.; Nitta, K.; Yoshioka, Y.; Nomura, H. 1983: Antitumor activity of tetrahydro-2-furanyl- and tetrahydro-2-pyranyl-glucans obtained by chemical modification of (1 leads to 3)-beta-D-glucan from Alcaligenes faecalis var. myxogenes IFO 13140 and its lower molecular weight glucans Cancer Treatment Reports 67(3): 275-280
Hishmat, O.H.; Hashim, A.A.; Shalash, M.R.; Nawito, M. 1972: Some benzofuran-carboxamide derivatives with narcotic and analgesic activity Arzneimittel-Forschung 22(1): 158-160
Malec, D.; Langwiński, R. 1981: Central action of narcotic analgesics. VIII. the effect of dopaminergic stimulants on the action of analgesics in rats Polish Journal of Pharmacology and Pharmacy 33(3): 273-282
Jezdinský, J. 1978: Analgesic activities of some commonly used analgesics and analgesic mixtures in animal experiments Activitas Nervosa Superior 20(4): 291-293
Herdewijn, P. 1995: Structure-activity relation study of anti-herpes associations with a 2'-deoxyuridine basic structure Verhandelingen - Koninklijke Academie Voor Geneeskunde van Belgie 57(6): 601-615
Mokrosz, J.L.; Dukat, M.; Misztal, S.; Chojnacka-Wójcik, E.; Tatarczyńska, E. 1990: Structure-activity relationship studies of CNS agents. Part 1: the Free-Wilson analysis of acute toxicity and sedative effect of some 1,2,3,4-tetrahydro-beta-carbolines Die Pharmazie 45(10): 765-767
Fitzgerald, J. 1991: Narcotic analgesics in renal failure Connecticut Medicine 55(12): 701-704
Schulze, W.; Horn, G. 1970: Correlations between chemical structure and biological activity of azomethines with nitrogen-mustard-groups on Ehrlich ascites tumor in albino mice. 3. Activation of N-mustard-azomethines by cells of Ehrlich ascites carcinoma Arzneimittel-Forschung 20(3): 329-335
Chang, K.J.; Wei, E.T.; Killian, A.; Chang, J.K. 1983: Potent morphiceptin analogs: structure activity relationships and morphine-like activities Journal of Pharmacology and Experimental Therapeutics 227(2): 403-408
Carron, J.D. 2014: Avoiding narcotic analgesics in young children Journal of the Mississippi State Medical Association 55(7): 235-236
Budhiraja, R.D.; Bala, S.; Kaur, A.H.; Garg, K.N. 1980: A simple technique of screening narcotic analgesics Indian Journal of Physiology and Pharmacology 24(3): 243-244
Fang, H.J.; Duan, H.J.; Zhou, T.H.; Chen, C. 1989: Studies on the analysis of some narcotic analgesics and CNS-stimulants Yao Xue Xue Bao 24(10): 759-768