Anti-tuberculous drugs and sideroblastic anaemia
Sharp, R.A.; Lowe, J.G.; Johnston, R.N.
British Journal of Clinical Practice 44(12): 706-707
1990
ISSN/ISBN: 0007-0947 PMID: 2102203 Document Number: 356766
Two cases of sideroblastic anaemia associated with antituberculous therapy are reported. The first, in whom there was a constitutional chromosomal abnormality and peripheral neuropathy, recovered on withdrawal of isoniazid and pyridoxine treatment. The other, who had been given a four-drug combination including isoniazid and pyrazinamide and recovered on the withdrawal of isoniazid alone, highlights the increasing likelihood of this complication in patients treated for tuberculosis, since this drug combination has regained popularity in recent years.