DRESS syndrome or reaction to drugs with eosinophilia and systemic symptoms associated to anti-tuberculosis drugs
Fernández de Córdova-RodrÃguez1, L.R.é; Guzmán-Guillén, K.A.; Fernández de Córdova-Aguirre, J.C.
Revista Alergia Mexico 62(2): 149-156
2015
ISSN/ISBN: 0002-5151 PMID: 25958379 Document Number: 16403
Tuberculosis has increased all over the world. This paper reports the case of a male patient with tuberculous meningitis, spinal tuberculosis (Pott's disease) and severe adverse reactions to antituberculosis drugs. He had skin rash, hepatitis, eosinophilia and fever; all these signs make the diagnosis of DRESS syndrome. This syndrome is caused by a severe hypersensitivity reaction to different drugs. It is usually caused by anticonvulsants, sulfonamides and some antiviral drugs, among other drugs. Anti-tuberculosis drugs can also cause this potentially fatal syndrome. The importance of surveillance for early detection and treatment of adverse drug reactions is emphasized.
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