Hemostatic disorders in patients with Schoenlein-Henoch syndrome
Mishkova, R.; Kudeva, K.; Petrova, E.
Klinicheskaia Meditsina 68(6): 47-49
1990
ISSN/ISBN: 0023-2149 PMID: 2214638 Document Number: 356605
Several indices of coagulation and fibrinolysis were studied in 54 patients suffering from Schönlein-Henoch disease. A significant prolongation of platelet aggregation was found in parallel with a decrease of AT III and plasminogen and an increase of the fibrin monomer complexes. Consequent to heparin treatment controlled by measurements of residual thrombin activity, the indices showed a trend towards normalization. The dynamic monitoring of the above indices can be used for an overall assessment of the heparin treatment.