Results of liver function tests in abomasal displacement and ketosis of cattle

Gül, Y.; Gründer, H.D.

Deutsche Tierärztliche Wochenschrift 97(3): 126-130

1990


ISSN/ISBN: 0341-6593
PMID: 2331971
Document Number: 354861
Totally 187 cows were used in this research. 101 of these had left and 60 right abomasal displacement. The rest of them had ketosis. Blood and urine samples were collected from all of the cows for laboratory analyses. The amount of bile acid and total bilirubin and activity of aspartataminostransferases (AST) in blood samples and the amount of ketone in the urine samples were determined. The results obtained from this study were as follows: The mean value of bile acid, total bilirubin and AST-activity were 38.37 .mu.mol/l, 13.06 .mu.mol/l and 92.26 U/l in right abomasal displacement cows and 37.93 .mu.mol/l 14.39 .mu.mol/l and 68.39 U/l in left abomasal displacement cows respectively. Although important differences (P < 0.05) were detected in AST-values between these three groups of diseases, there were no significant differences in bile acid and total bilirubin. There was a correlation between total bilirubin and bile acid and total bilirubin and AST in the right and left abomasal displacement cows. Same correlation was determined between total bilirubin and AST in acetonemic cows. But there was no correlation between total bilirubin and bile acid in acetonemic cows and between bile acid and AST in abomasal displacement and acetonemic cows. A very important connection was determined between the amount of total bilirubin and degree of the acetone in the urine (P < 0.001) of the left abomasal displacement cows. The same connection (P < 0.05) was determined between the degree of the acetone in the urine and AST-activity in the same cows. Increased bile acid in 26 cows, increased total bilirubin in 45 cows and increased AST-value in 23 cows were determined from 60 right abomasal displacement cows. 33, 74 and 21 cows out of 97 left abomasal displacement cows showed increased bile acid, total bilirubin and AST-value respectively. 11,23 and 6 out of 26 acetonemic cows indicated increased bile acid, total bilirubin and AST-value. An although important important difference was determined in AST-activity between blood taking before and three days after operative abomasal displacement correction, differences in total bilirubin and bile acid were not found.

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