The molecular level of general pathological processes
Pigarevskiĭ, V.E.
Arkhiv Patologii 52(1): 5-11
1990
ISSN/ISBN: 0004-1955 PMID: 2186720 Document Number: 353899
The knowledge of the molecular level of the general pathologic processes is a prerequisite for new concepts realized in the practice. The molecular destructive processes, programmed cell death and inflammation are considered as examples. The hypothesis of the catastrophe of errors is reviewed, the results of studies on the limited proteolysis reaction as well as intracellular destructive processes compatible with the life of cell are summarized. The concept of nonphagocytic tissue resistance and resorptive cellular resistance as a peculiar type of nonspecific protective reactions in the infectious inflammation is substantiated.