Role of GABA receptors in pathological processes
Tiurenkov, I.N.; Perfilova, V.N.
Eksperimental'naia i Klinicheskaia Farmakologiia 74(2): 47-52
2011
ISSN/ISBN: 0869-2092 PMID: 21476287 Document Number: 651264
The review presents data indicative that both qualitative and quantitative changes in the structure of GABA--receptor complexes can lead to neurologic, mental, vegetotropic, somatic, hormonal and other disorders. The knowledge of structure of GABA receptors, their functions, and participation in the development of pathological states can promote the search for new selective synthetic substances capable of affecting receptor target, which opens ways to creating new highly effective and safe preparations for the treatment of various diseases.