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The toxicity of a prometryne/simazine combination in the lactation stage of rats

Messow, A.; Benkwitz, F.; Hellwig, A.

Zeitschrift für die Gesamte Hygiene und ihre Grenzgebiete 36(3): 170-173

1990

ISSN/ISBN: 0049-8610
PMID: 2336864
Document Number: 352865
The postnatal effect of a combination of Prometryne and Simazine was analyzed in rats. Lactating rats were administered from 5 through 10 d pp. The effect on rat pups were characterized by reflex development, behavioural toxicological tests, and selected biochemical investigations. Distinct effects were observed on body weight, neuro-muscular maturation, and somatic development. There were also significant differences in the content of C-reactive protein and the number of white blood cells.

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