Effect of pirazolac on prostanoid synthesis by human gastric mucosa in vitro

Tavares, I.A.; Bennett, A.

Drugs under Experimental and Clinical Research 16(1): 1-6

1990


ISSN/ISBN: 0378-6501
PMID: 2115830
Document Number: 352735
Pirazolac concentration-relatedly inhibited the accumulation of prostanoids in incubates of human gastric mucosa, but this inhibition was less than that by indomethacin and other commonly used non-steroidal anti-inflammatory drugs. This difference may explain the claim that pirazolac is less damaging to the stomach.

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