Use of amphotericin B in immunosuppressed patients with cancer. Part Two: Pharmacodynamics and nursing implications
Holtzclaw, B.J.; Rutledge, D.N.
Oncology Nursing Forum 17(5): 737-742
1990
ISSN/ISBN: 0190-535X PMID: 2251192 Document Number: 351371
Nursing care of patients receiving amphotericin B (AmB) must address the underlying condition of the immunosuppressed patient with cancer and the iatrogenic responses induced by the drug. This review, the companion to "Part One: Pharmacology and Toxicities," focuses on nursing actions that consider both the drug's specific pharmacodynamics and the altered human responses caused by disease and therapy. Maximization of drug effectiveness and minimization of drug toxicity are key care goals.