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Pharmacokinetics and pharmacodynamics of a short- and long-acting theophylline medication (Theolair and Theolair retard) in normals and patients with COLD. Part III: Plasma cyclic AMP

Kreukniet, J.; Utama, I.; Hamelink, M.L.

International Journal of Clinical Pharmacology Therapy and Toxicology 21(6): 297-300

1983

ISSN/ISBN: 0174-4879
PMID: 6309681
Document Number: 216322
Supporting evidence was found for the beta-blockade theory of Szentivanyi. Asthmatics (n = 6) showed lower basal plasma cyclic AMP levels and lower cyclic AMP levels after administration of a short- and long-acting theophylline preparations (Theolair and Theolair retard) than normals (n = 6) did. No difference was found in this respect between Theolair and Theolair retard. Basal cyclic AMP levels showed a diurnal variation, with highest levels in the morning which gradually decreased during the day. The correlation of the plasma cyclic AMP levels with the lung function change after stimulation with theophyllines in asthmatics was rather poor. This is probably caused by the rather low changes in plasma cyclic AMP levels.

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Domson, J.F.; Hein, E.W.; Sheen, A.; Sly, R.M. 1979: Comparison of Theolair SR and Theo-Dur tablets Annals of Allergy 43(4): 220-222
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Köhler, E.; Sollich, V.; Schuster, R. 1993: Compliance of children with bronchial asthma in long-term therapy with theophylline retard preparations Kinderarztliche Praxis 61(6): 207-210
Chalabala, M.; Starha, L. 1970: Peroral, compounded long-acting drugs. 3. Tablets coated with Eudragite retard Ceskoslovenska Farmacie 19(5): 184-186
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Tinkelman, D.G.; Edelman, L.; Decouto, J.; Maloch, L.D.; Spangler, D.L. 1985: The effect of diet on the metabolism of long acting theophylline Annals of Allergy 54(4): 280-283
Mulkey, P.M.; Murphy, J.E.; Shleifer, N.H. 1983: Steady-state theophylline pharmacokinetics during and after short-term cimetidine administration Clinical Pharmacy 2(5): 439-441
Das, M.; Anand, A.; Hossain, B.; Ansari, S. 2022: Inequalities in short-acting reversible, long-acting reversible and permanent contraception use among currently married women in India Bmc Public Health 22(1): 1264
Widecka, K.; Krzyzanowska-Swiniarska, B.; Ciechanowski, K.; Goździk, J.; Czekalski, S. 1993: Plasma concentrations of atrial natriuretic peptide and cyclic guanosine monophosphate in patients with hyperthyroidism before and after short-term treatment with methimazole Endokrynologia Polska 44(1): 65-71
Benzi, L.; Marchetti, P.; Carriero, P.L.; Ciccarone, A.M.; Di Cianni, G.; Giannarelli, R.; Giovannitti, M.G.; Navalesi, R. 1987: Long-term therapy with biosynthetic human insulin: importance of short-acting/intermediate-acting insulin ratio on determining efficacy of treatment Drugs under Experimental and Clinical Research 13(5): 321-325
Weiss, M.; Sziegoleit, W.; Machill, K.; Hafemeister, G.; Förster, W. 1980: Relationship between the pharmacokinetics of a short-acting antiarrhythmic drug and its effects: studies with Falirytmin International Journal of Clinical Pharmacology Therapy and Toxicology 18(6): 237-241
Rao, Y.V.; Reddy, K.S.; Wasir, H.S. 1991: Assessment of antianginal efficacy of long-acting sustained release isosorbide dinitrate in comparison with short-acting isosorbide dinitrate Indian Heart Journal 43(2): 97-100
Davey, L.A.; Ferber, M.T.; Kaye, B. 1985: Comparison of the serum pharmacokinetics of a long acting and a conventional oxytetracycline injection Veterinary Record 117(17): 426-429
Wemhöner, S.; Oellerich, M.; Sybrecht, G. 1981: Theophylline therapy in obstructive respiratory diseases. 1. Bioavailability and pharmacokinetics of various theophylline preparations Praxis und Klinik der Pneumologie 35(1): 36-41
Dayer, P.; Deom, A.; Roth, M. 1982: Absorption of theophylline: pharmacokinetics of 2 water-alcohol solutions of theophylline Pharmaceutica Acta Helvetiae 57(1): 27-32
Slapke, J.; Hummel, S.; Wilke, A.; Wenz, W.; Meister, W.; Förster, R.; Wiesner, B.; Rentsch, E.; Nussbücker, B. 1988: Clinical use of theophylline retard Oranienburg Zeitschrift für Erkrankungen der Atmungsorgane 170(1): 49-53
Berkalov, M.I.; Timerbaev, V.K.; Valetova, V.V.; Davydova, N.A. 2008: Pharmacokinetics and pharmacodynamics of ketamine in patients in the surgical treatment of abdominal diseases Anesteziologiia i Reanimatologiia 1: 66-70
Nakano, J.; Ishii, T. 1970: Effect of ketone bodies on hormone-, theophylline- and dibutryl cyclic AMP-induced lipolysis and on cyclic AMP-phosphodiesterase Research Communications in Chemical Pathology and Pharmacology 1(4): 485-496
Villani, F.; Bohnet, A.; Sakellaridès, E.; Schelling, J.L. 1975: Urinary concentration and antibacterial effect of short and long acting tetracycyline Schweizerische Medizinische Wochenschrift 105(11): 341-344