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Nuclear DNA content in tumors of the colon and rectum. Relationship between ploidy and site of the neoplasm

Larghero, G.C.; Ottonello, M.; Testa, T.; Scarpettini, S.; Abbondati, A.; Capponi, G.

Minerva Chirurgica 45(5): 247-250

1990

ISSN/ISBN: 0026-4733
PMID: 2377295
Document Number: 351169
The DNA distribution pattern was determined 30 colo-rectal carcinomas. The DNA content in individual cells was measured according to a cytophotometric method based on light transmission measurement of Feulgen-stained nuclei. The DNA non diploid carcinomas were significantly more common from the left (descending and sigmoid) colon and rectum (P = 0.0002). No relationship existed between DNA pattern and age, sex, Dukes' stage, tumor grade.

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