The rapid diagnosis of chronic nonspecific lung diseases
Makarian, E.A.; Drozhennikov, V.A.
Laboratornoe Delo 10: 16-19
1990
ISSN/ISBN: 0023-6748 PMID: 1704447 Document Number: 350738
Rapid methods for the detection of viral antigens and immunoglobulins in nasal and bronchial washings from patients with chronic nonspecific pulmonary diseases (CNPD) are described. These methods are based on viral antigen and immunoglobulin agglutination with cellulose particles sensitized with specific sera and gamma-globulin fractions. The investigation takes just 3-5 min. Respiratory syncytial virus, influenza A and B, parainfluenza viruses, adenoviruses, immunoglobulins G and M, and immunoglobulin A in low levels are detectable with the use of the described methods. Studies carried out over the course of treatment helped detect low titers of viral antigens and IgG and IgM and a high titer of IgA.