The immunohistochemical demonstration of intracytoplasmic estradiol in colorectal neoplasms
Arena, F.; Faraone, V.; Crisafulli, C.; De Gaetano, C.; Di Vincenzo, C.; Bartolo, V.; Di Mauro, S.
Chirurgia Italiana 42(1-2): 19-26
1990
ISSN/ISBN: 0009-4773 PMID: 2076583 Document Number: 350532
Intracytoplasmic estradiol content was studied retrospectively using immunohistochemical procedures in tissue samples from subjects suffering from colorectal cancer. The results obtained reveal the presence of intracytoplasmic estradiol in cancer tissue. In precancerous lesions this presence is rarer and inconstant. Estradiol was not detected in the healthy tissue examined. These data suggest that such tumours may depend to some degree on endocrine factors.