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International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/3. Animal studies suggesting involvement of mutagen/carcinogen exposure in atherosclerosis

Wakabayashi, K.

Mutation Research 239(3): 181-187

1990

ISSN/ISBN: 0027-5107
PMID: 2233825
Document Number: 349941
It is very important to elucidate the causative agents of atherosclerosis because coronary heart disease and cerebrovascular disease are the main causes of death in the developed countries. The evidence for a monoclonal origin of atherosclerotic plaques in humans prompted the study of the involvement of mutagens/carcinogens in the development of atherosclerosis. Polycyclic hydrocarbons, including 7,12-dimethylbenzpyrene, were shown to act as initiators and/or accelerators in atherosclerotic plaque formation in the chicken, pigeon and mouse. Radiation and oxygen radicals were also demonstrated to be involved in the development of atherosclerosis in animals.

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Matsunaga, E. 1983: International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC working paper 5/5. Perspectives in mutation epidemiology. 5. Modern medical practice versus environmental mutagens: their possible dysgenic impact Mutation Research 114(3): 449-457
von Wartburg, J.P. 1987: International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC Working Paper No. 15/5. Acute aldehyde syndrome and chronic aldehydism Mutation Research 186(3): 249-259
Czeizel, A.; Kis-Varga, A. 1987: International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC working paper no. 4. Mutation surveillance of sentinel anomalies in Hungary, 1980-1984 Mutation Research 186(1): 73-79
de Serres, F.J. 1988: International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC topic No. 2. Heterozygous effects of multilocus deletions Mutation Research 196(1): 95-99
Ehling, U.H.; Averbeck, D.; Cerutti, P.A.; Friedman, J.; Greim, H.; Kolbye, A.C.; Mendelsohn, M.L. 1983: International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC publication no. 10. Review of the evidence for the presence or absence of thresholds in the induction of genetic effects by genotoxic chemicals Mutation Research 123(3): 281-341
Richard, A.M. 1994: International Commission for Protection Against Environmental Mutagens and Carcinogens. Application of SAR methods to non-congeneric data bases associated with carcinogenicity and mutagenicity: issues and approaches Mutation Research 305(1): 73-97
Montesano, R.; Rajewsky, M.F.; Pegg, A.E.; Miller, E. 1982: Development and possible use of immunological techniques to detect individual exposure to carcinogens: International Agency for Research on Cancer/International Programme on Chemical Safety Working Group Report Cancer Research 42(12): 5236-5239
Int Comm Radiol Prot Comm 4 1973: Implications of commission recommendations that doses be kept as low as readily achievable a report of international commission of radiological protection committee 4 adopted by the commission in april 1973 Radiation Protection ICRP (International Commission on Radiological Protection) Publication 22: 1-18
Forni, A. 1984: Chromosomal aberrations in monitoring exposure to mutagens-carcinogens Iarc Scientific Publications 1984(59): 325-337
Tschaeche, A.N. 1997: Guidelines on limits of exposure to broad-band incoherent optical radiation (0.38 to 3 microM). International Commission on Non-Ionizing Radiation Protection Health Physics 73(3): 539-554
Tsuchiya, T. 1980: Radiation protection and recommendation of the international commission on radiological protection Journal of UOEH 2(3): 393-400
Scales, M.D.; Mahoney, K. 1991: Animal toxicology studies on new medicines and their relationship to clinical exposure: a review of international recommendations Adverse Drug Reactions and Toxicological Reviews 10(3): 155-168
Iakovenko, K.I.; Tarusina, T.O.; Kuleshov, N.P. 1976: Individual variations in the frequency of chromosome aberrations following exposure to chemical mutagens. II. Interindividual variation in the frequency of chromosome aberrations in the presence of different mutagen concentrations Genetika 12(12): 139-143
1971: Commission of the European Community prepares a program of action on the matter of environmental protection Minerva Medica 62(59-60 Suppl): 9-10
Wagner, B.M. 1990: The mutagen = carcinogen controversy Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology Inc 3(5): 555-556
Palmiter, C.C.; Shleien, B. 1979: Critique of the international atomic energy agency international labor office who nea international committee on radiological protection topical seminar on the practical implications of the international committee on radiological protection recommendations 1977 and revised international atomic energy agency basic safety standards for radiation protection Health Physics 37(6): 815
Eisenlohr, H.H.; Abedin-Zadeh, R.; Nagl, J. 1973: Working program of the IAEC (International Atomic Energy Commission), Dosimetry Section in the field of medical use of irradiation Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 1973(0): Suppl: 351-2
Izmerov, N.F. 1981: Hygienic optimization of working conditions and environmental protection Vestnik Akademii Meditsinskikh Nauk SSSR 3: 76-80
Epstein, S.S. 1976: Regulatory aspects of occupational carcinogens: contrasts with environmental carcinogens Iarc Scientific Publications 13: 389-402
Morimoto, K.; Koizumi, A. 1985: A carcinogens--methods for detecting environmental muta/carcinogens Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(4): 789-797