Intravaginal bacterial flora in patients with uterine cervical cancer, with special reference to Gardnerella vaginalis
Ito, K.; Tamaya, T.; Watanabe, K.; Ueno, K.
Nihon Sanka Fujinka Gakkai Zasshi 42(11): 1551-1555
1990
ISSN/ISBN: 0300-9165 PMID: 2273311 Document Number: 348216
In a total of 18 subjects, comprising 16 cases of uterine cervical cancer (4 cases, stage Ib; 1 case, stage IIa; 11 cases, stage IIb) and 2 cases of cervical dysplasia, the intravaginal bacterial floras, including Gardnerella vaginalis (G. vaginalis) and Mobiluncus spp., were investigated. In uterine cervical cancer, there were mixed bacterial flora of aerobes and anaerobes but what is of note is that G. vaginalis was detected in 7 out of 16 cases of uterine cervical cancer and in 1 out of 2 cases of dysplasia. The number of G. vaginalis present was far greater than that of the other coexisting species. In contrast, none of the Mobiluncus spp. was detected. Since G. vaginalis was detected at a high incidence in uterine cervical cancer and dysplasia, the possibility of a relationship between G. vaginalis and uterine cervical cancer was suggested.