Protective effect of ascorbic acid in cells of people exposed to cobalt chloride

L'vova, G.N.; Chopikashvili, L.V.; Vasil'eva, I.M.; Zasukhina, G.D.

Genetika 26(7): 1316-1319

1990


ISSN/ISBN: 0016-6758
PMID: 2121602
Document Number: 347955
The workers contacting with cobalt chloride for 10 years and more have been receiving 50 mg ascorbic acid for 30 days. DNA repair was analysed after this procedure in lymphocytes cultivated in vitro according to following criteria: reactivation and induced mutagenesis of vaccinia virus as well as formation of DNA breaks and their resynthesis upon treatment with cobalt chloride and 4-nitro-quinoline-1-oxide.

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