A study of peripheral blood lymphocyte subsets in patients with bladder tumors
Matsuda, H.; Nakanishi, A.; Ishihara, H.; Umejima, S.; Tsujihashi, H.; Akiyama, T.; Kurita, T.
Hinyokika Kiyo. Acta Urologica Japonica 35(7): 1129-1134
1989
ISSN/ISBN: 0018-1994 PMID: 2801404 Document Number: 346147
The analysis of peripheral blood lymphocytic subpopulations was conducted with 16 bladder tumor patients. Lymphocytes were collected centrifugally from the peripheral blood of preoperative patients with bladder tumors, and measured by means of flow cytometry. Among the stages of the bladder tumor patients, there were no clear relationships in the ratio between T cells and B cells. However, with the progression in stages a rise in OKT 8, as well as the lowering of the OKT 4/OKT 8 ratio were discerned. In relation to pTis, Leu 7 showed a higher value than that in other groups with advanced invasion. This suggests that in measurements of lymphocyte subsets in peripheral blood, it will to a certain extent be possible to estimate the preoperative immunological competence of bladder tumor patients.