Changes of peripheral lymphocyte subsets in patients with oral squamous carcinoma
Moroyama, T.; Endo, K.; Hazutani, J.; Iwao, I.; Shiratsuki, T.; Mitsui, K.; Sugihara, K.; Okahara, Y.; Hara, J.; Sakamoto, T.
Gan no Rinsho. Japan Journal of Cancer Clinics 31(2): 117-121
1985
ISSN/ISBN: 0021-4949 PMID: 3157809 Document Number: 243022
The distribution of peripheral lymphocyte subsets of 32 patients, who had undergone surgical removal of squamous carcinoma and have evaded recurrence was studied using OK series monoclonal antibodies. The T-lymphocyte subpopulation was reduced in patients who were tumor free for more than 3 years. The helper/inducer T-cell subpopulation was reduced in most of the patients studied, whereas little change was observed in the subpopulation of suppressor/cytotoxic T cells. Consequently the ratio of OKT 4+/OKT 8+ was reduced in accordance with the tumor free period.