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Clinical efficacy of clarithromycin in the field of pediatrics

Ogura, H.; Kubota, H.; Nomura, I.; Tomoda, T.; Araki, K.; Ogura, Y.; Kurashige, T.

Japanese Journal of Antibiotics 42(2): 401-410

1989

ISSN/ISBN: 0368-2781
PMID: 2526253
Document Number: 345818
A new macrolide antibiotic, clarithromycin (TE-031, A56268), was studied for its clinical efficacy in the field of pediatrics. Patients treated were infants and children ranging from 2 months to 11 years old suffering from acute bronchitis in 5 cases, acute tonsillitis in 2 cases, Mycoplasma pneumonia in 2 cases, pertussis in 6 cases, scarlatina in 1 case and acute enteritis in 2 cases, a total of 18 cases. TE-031 was administered 19.7 .apprx. 43.5 mg/kg in daily doses and lengths of treatment ranged from 4 to 19 days. As regards to its clinical efficacy, good or excellent results were obtained in all cases: excellent in 11 cases and good in 7 cases. No clinical side effects nor abnormal laboratory test values obviously attributable to TE-031 were observed.

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