Determination of antibodies in blood serum of patients with pulmonary tuberculosis using mycobacterial antigen affinity isolation
Gil'burd, B.S.; Markov, A.N.; Fondaminskaia, L.D.
Problemy Tuberkuleza 7: 52-55
1989
ISSN/ISBN: 0032-9533 PMID: 2508082 Document Number: 345761
Possible use of radio- and enzyme immunoassays (RIA and EIA, respectively) in serodiagnosis of tuberculosis with antigen BCG isolated by affinity was studied in comparison to the use of the routine antigen PPD. The specific IgG antibodies were determined in serum specimens of 150 patients with various forms of pulmonary tuberculosis and 50 healthy donors. A statistically reliable difference in the efficiency of tuberculosis serodiagnosis (high levels of specificity and sensitivity) by the RIA and EIA with using antigen BCG isolated by affinity was observed.