Experimental heterotransplantation of human ovarian tumors in nude mice
Wei, L.H.
Zhonghua Fu Chan Ke Za Zhi 24(1): 32-34; 58-59
1989
ISSN/ISBN: 0529-567X PMID: 2758902 Document Number: 344765
Human ovarian tumors tissue taken from four surgical specimen were transplanted subcutaneously into female nude mice. The primary tissue transplantations were all successful, and the mean survival time was 15 weeks. One of the four ovarian carcinomas has been successfully transplanted to the 9th passage. Time needed for each passage was 4-6 weeks. The transplanted tumors examined histologically, cytologically and by electro-microscope, resembled the original ovarian cancer. Immunohistochemical tests were positive. Chromosome number was subdiploid and aneuploid.