Non-ulcer dyspepsia and Campylobacter pylori
Restellini, A.; Hofstetter, J.R.
Schweizerische Rundschau für Medizin Praxis 78(25): 715-717
1989
ISSN/ISBN: 1013-2058 PMID: 2667070 Document Number: 344304
Dyspepsia, defined as chronic vague upper abdominal symptoms, is a common condition. The pathogenesis of this syndrome remains poorly understood. The etiologic role of Campylobacter pylori and associated gastritis remain controversial though this organism colonizes the gastric antrum in one third to one half of patients with non-ulcer dyspepsia. Recent studies raise the prospect that treatment with bismuth improves gastritis and is successful in treating symptoms in the Campylobacter pylori positive and negative patients. To determine if Campylobacter pylori causes dyspepsia requires proof that long term eradication of the organism heals gastritis and abolishes symptoms.