Testing of a hyperimmune serum in calves infected intranasally with Mycoplasma bovis
Brys, A.; Pfützner, H.
Archiv für Experimentelle Veterinarmedizin 43(5): 677-683
1989
ISSN/ISBN: 0003-9055 PMID: 2533483 Document Number: 342750
Mycoplasma (M.) bovis hyperimmune serum was subcutaneously injected to 16 of 26 calves repeatedly intranasally infected with M. bovis, during and/or after experimental infection. Antibody titres between 1:32 and 1:256 were recorded by means of indirect haemagglutination from the calves treated. Transmission of film-inhibitory antibodies failed to work. Neither clinical manifestations nor pathologico-anatomic alterations to the lungs of experimentally infected animals were mitigated by hyperimmune serum treatment. M. bovis, in high germ counts, was re-isolated from nasal swabs, trachea, pulmonary lymph nodes, and inflammatory lung tissue of both treated and untreated calves.