Top Abstract Purchase Related
Home
>
Node
>
Subnode

Basic studies on optimal intra-arterial infusion rate of cisplatin

Kishimoto, S.; Fukushima, S.; Hayashi, Y.; Nakano, M.; Miyazaki, K.; Okamura, H.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 16(8 Part 2): 2788-2791

1989

ISSN/ISBN: 0385-0684
PMID: 2782889
Document Number: 342578
The relationship between platinum concentration in tissues, free CDDP concentration in plasma and infusion rate was investigated in order to determine the optimal intra-arterial infusion rate of CDDP for chemotherapy of cervical carcinoma. Platinum concentrations in uterus were in the same level in the intravenous infusion groups independent of the infusion rate. In the intra-arterial infusion groups, platinum concentrations in the uterus increased as the infusion rate decreased from 24 to 0.8 mg/hr, although Cmax and AUC were decreased. Platinum concentrations in the ovary supplied by another artery were not influenced by the intra-arterial infusion rate. It is suggested that uptake of CDDP in the targeted tissues can be increased by control of intra-arterial infusion rate.

Document emailed within 1 workday
Secure & encrypted payments

Hara, K.; Tada, M.; Naruse, S.; Soma, Y.; Kojima, Y.; Kurata, H.; Tanaka, K.; Tsuji, S. 2003: Two cases of lumbosacral radiculopathy after intra-arterial infusion of cisplatin for treatment of uterine cancer Rinsho Shinkeigaku 43(1-2): 26-30
Taguchi, T.; Kondo, M.; Tanikawa, K.; Nakamura, H.; Okawa, T.; Ogawa, N. 1993: Comparative clinical study in metastatic liver cancer between intra-arterial infusion of mitomycin C alone and intra-arterial infusion of mitomycin C combined with PJ-203 (degradable starch microspheres) Gan to Kagaku Ryoho. Cancer and ChemoTherapy 20(13): 2027-2035
Uchida, J.; Okada, H.; Ohguchi, N.; Kawa, G.; Koyama, Y.; Mikami, O.; Kawamura, H.; Ohhara, T.; Matsuda, T. 1997: Comparison of side effects caused by intra-arterial and intravenous infusion of M-VAC (methotrexate, vinblastine, adriamycin and cisplatin) for urothelial cancer Hinyokika Kiyo. Acta Urologica Japonica 43(9): 637-640
Takeuchi, K.; Taniguchi, H.; Miyata, K.; Ueshima, Y.; Okano, S.; Oguro, A.; Sawai, K.; Takahashi, T. 1992: Recurrence and survival rate of advanced gastric cancer after preoperative cisplatin intra-arterial injection therapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 19(10 Suppl): 1686-1689
Roth, J.; Schumacher, K.A.; Safi, F. 1989: Computed tomographic and angiographic studies of arterial liver perfusion following intra-arterial infusion chemotherapy using 5-fluoro-2-deoxyuridine Rontgen-Blatter; Zeitschrift für Rontgen-Technik und Medizinisch-Wissenschaftliche Photographie 42(2): 80-84
Tada, I.; Kobayashi, M. 1985: Basic and clinical study of liver cancer using intra-arterial infusion of an emulsion of the oily contrast medium lipiodol with 5-FU Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(10): 1938-1939
Masuyama, M.; Taniguchi, H.; Takeuchi, K.; Miyata, K.; Koyama, H.; Tanaka, H.; Higashida, T.; Koishi, Y.; Mugitani, T.; Yamaguchi, T. 1994: Recurrence and survival rate of advanced gastric cancer after preoperative EAP-Ii intra-arterial infusion therapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(13): 2253-2255
Gottlob, R.; Hugeneck, J. 1982: Intra-arterial infusion. I. Kinetic studies on local blood levels Wiener Medizinische Wochenschrift 132(18): 415-421
Itano, S.; Hirai, K.; Kajiwara, M.; Ijuin, H.; Yoshiyama, Y.; Yoshida, T.; Sakata, K.; Ono, N.; Noguchi, H.; Sakai, T. 1994: A study of the drug distribution on intra-hepatic arterial infusion chemotherapy; how much difference between continuous infusion and rapid infusion? Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(13): 2136-2139
Tomizawa, Y. 1988: Experimental studies on pharmacokinetics and tissue concentration of cis-dichlorodiammineplatinum (II) (CDDP) by intra-arterial infusion with hemostasis Nihon Seikeigeka Gakkai Zasshi 62(6): 627-633
Fujimoto, T.; Yoshimatsu, K.; Yokomizo, H.; Umehara, A.; Watanabe, K.; Otani, T.; Matsumoto, A.; Osawa, G.; Itagaki, H.; Ogawa, K. 2007: Extra- and intra-hepatic metastasis successfully treated with alternative chemotherapy with hepatic arterial infusion and systemic intravenous infusion after responding to hepatic metastasis from colon cancer by hepatic arterial infusion--a case report Gan to Kagaku Ryoho. Cancer and ChemoTherapy 34(12): 1976-1978
Izawa, H.; Nomura, S.; Inoue, H. 1988: Intra-arterial chemotherapy of ovarian cancer using a subcutaneously embedded reservoir--a case showing remarkable response to intermittently repeated low-dose intra-arterial infusion chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 15(1): 147-150
Watanabe, M.; Tsuchiya, M.; Takita, W.; Otsuka, Y.; Tamura, A.; Yamazaki, K.; Koshino, H.; Kurihara, A.; Kaneko, H.; Teramoto, T. 2006: Case report of a liver metastasis from rectal cancer achieving complete response (CR) by a combination of intra-hepatic arterial infusion of irinotecan (CPT-11) with degradable starch microspheres (DSM) and weekly high-dose intra-hepatic arterial chemotherapy with 5-FU Gan to Kagaku Ryoho. Cancer and ChemoTherapy 33(10): 1485-1488
Kishimoto, S.; Sasaki, Y.; Imaoka, S.; Nakano, H.; Furukawa, H.; Ishikawa, O.; Ohigashi, H.; Kabuto, T.; Kameyama, M.; Hiratsuka, M. 1994: A case of huge liver metastasis from jejunal leiomyosarcoma completely controlled by intra-arterial and intra-portal vein infusion chemotherapy following hepatectomy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(13): 2198-2201
Juhan, C.; Haupert, S.; Miltgen, G.; Girard, N.; Dulac, P. 1991: A new intra arterial rt-PA dosage regimen in peripheral arterial occlusion: bolus followed by continuous infusion Thrombosis and Haemostasis 65(5): 635
Une, Y.; Uchino, J.; Yasuhara, M.; Misawa, K.; Kamiyama, T.; Shimamura, T.; Sato, N.; Nakajima, Y.; Hata, Y. 1993: Intra-arterial infusion chemotherapy on unresectable hepatocellular carcinoma under occlusion of hepatic arterial flow Clinical Therapeutics 15(2): 347-354
Garcia, R.; Saroyan, R.M.; Senkowsky, J.; Smith, F.; Kerstein, M. 1990: Intraoperative intra-arterial urokinase infusion as an adjunct to Fogarty catheter embolectomy in acute arterial occlusion Surgery Gynecology and Obstetrics 171(3): 201-205
Takatsuka, Y.; Fukushima, S.; Kokubu, I.; Endoh, S.; Sugitachi, A.; Kawahara, T. 1985: Intra-arterial infusion chemotherapy and transcatheter arterial chemo-embolization for patients with simultaneous bilateral breast cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(5): 1143-1146
Barinka, L. 1970: Hyperbaric cuff for intra-arterial infusion Rozhledy V Chirurgii: Mesicnik Ceskoslovenske Chirurgicke Spolecnosti 49(5): 266-269
Jaffe, N. 1984: Subcutaneous reaction due to intra-arterial infusion of anthracycline Cancer Treatment Reports 68(5): 818