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Computed tomographic and angiographic studies of arterial liver perfusion following intra-arterial infusion chemotherapy using 5-fluoro-2-deoxyuridine

Roth, J.; Schumacher, K.A.; Safi, F.

Rontgen-Blatter; Zeitschrift für Rontgen-Technik und Medizinisch-Wissenschaftliche Photographie 42(2): 80-84

1989

ISSN/ISBN: 0300-8592
PMID: 2522675
Document Number: 328323
Fifty patients with liver metastases from colorectal primaries underwent hepatic intraarterial chemotherapy using 5-fluoro-2-deoxyuridine as an antitumour agent. Repeated computed tomography and angiography of the liver was performed during a follow-up period of a year. Following six months of regional chemotherapy, arterial perfusion abnormalities of the liver were detected in 40 of the total of 50 patients. After one year of intraarterial chemotherapy normal arterial liver perfusion was found in only two patients. Histology revealed thrombotic occlusion or narrowing of hepatic arteries, respectively.

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