In vitro study of the influence of donor age, nature of mitogen and exposure to X-rays on the proliferation rate of human lymphocytes
Deknudt, G.; Van Autryve, L.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 183(6): 507-514
1989
ISSN/ISBN: 0037-9026 PMID: 2534955 Document Number: 341350
Proliferation of lymphocytes from donors belonging to 4 age groups (2, 25, 45 and 80 years) and exposed, in vitro, to 0 or 2 Gy of X-rays was studied in cultures stimulated by 3 different mitogens. Our results show that these 3 factors (age, irradiation and mitogen) play a role in the frequencies of cells observed in first, second, third or subsequent cell division in 48 or 72 h cultures.
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