Infection by Clonorchis sinensis in Asian immigrants in Brazil. Treatment with praziquantel
Leite, O.H.; Higaki, Y.; Serpentini, S.L.; Carvalho, S.A.; Amato Neto, V.; Torres, D.M.; Dias, R.M.; Chieffi, P.P.
Revista do Instituto de Medicina Tropical de Sao Paulo 31(6): 416-422
1989
ISSN/ISBN: 0036-4665 PMID: 2640514 Document Number: 339669
Fifteen adult patients with assymptomatic infection due to Clonorchis sinensis, diagnosed by coprological examination, were studied. They all came from Asia (twelve from Taiwan, two from South Korea and one from Hong Kong) and were examined at the Adolfo Lutz Institute and the Department of Infectious Diseases, School of Medicine, University of São Paulo, in São Paulo, Brazil. Six patients were women and nine men. All studied patients were admitted to hospital and treated with praziquantel (60 mg/kg). Previous to treatment and on the 15th, 30th and 60th days after praziquantel administration, patients were submitted to quantitative stool examinations, according to Kato-Katz's technique and to hematological and biochemical serum analysis. After a 60 day follow-up nine patients (60%) were negative for C. sinensis eggs in stools. Those not cured after praziquantel administration (six patients, 40%) revealed a sharp decline in faecal elimination of C. sinensis eggs.