Comparative study of the penetration of penicillin V, amoxicillin, cefaclor and josamycin in the tonsils
Bizet, C.; Pangon, B.; Moisy, N.; Bizet, J.; Bure, A.; Gehanno, P.
Pathologie-Biologie 37(4): 273-275
1989
ISSN/ISBN: 0369-8114 PMID: 2499865 Document Number: 339406
Fourty patients undergoing tonsillectomy for recurrent tonsillitis were administered penicillin V, amoxicillin, cefaclor or josamycin. Antibiotic concentrations in serum and tonsillar tissues were determined by microbiological assay. Cefaclor demonstrated a superior diffusion than penicillin V and amoxicillin, but nevertheless inferior to that of josamycin.
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