Predicting the effectiveness of antibiotic therapy in the treatment of gonorrhea
Stepanenko, V.I.; Koliadenko, V.G.; Voĭtsekhovskiĭ, V.G.; Gashinskiĭ, V.V.
Mikrobiolohichnyi Zhurnal 51(2): 103-106
1989
ISSN/ISBN: 0201-8462 PMID: 2761447 Document Number: 338970
A complex method is suggested to prognosticate the efficiency of treating gonorrheal urethritis in men with allowance for a preliminary determination of the cell respiration activity in agents. In the case of low indices of these processes, it is possible to stimulate aerobic processes in gonococci if applying for 4 days before the specific treatment daily subcutaneous injections of plasmol (a biostimulator) by the ascending scheme and local irrigation of the urethra by oxygen cocktails through irrigators of special design. The developed method has the author certificate (A. c. 1107867 USSR). Application of the method shortens significantly the terms of treatment, the number of the infection recurrences being considerably decreased. To accelerate the determination of the sensitivity to antibiotics the procedure of genococcus microcultivation in special chambers is applied which permits observing the growth and reproduction of microorganisms in the phase-contrast microscope.