Control of the effectiveness of antibiotic therapy by determining the antibacterial activity of the blood and cerebrospinal fluid
Căruntu, F.
Revista de Igiena Bacteriologie Virusologie Parazitologie Epidemiologie Pneumoftiziologie. Bacteriologia Virusologia Parazitologia Epidemiologia 27(2): 127-130
1982
ISSN/ISBN: 0376-4494 PMID: 7146758 Document Number: 187831
Determination of the antibacterial action of serum and the cerebrospinal fluid (CSF) is an excellent method for controlling the efficiency of antibioticotherapy in severe bacterial infections such as septicemia, endocarditis, meningitis. The author studied comparatively two methods for determining the antibacterial action of serum and CSF, namely dilution of the standard inoculum and diffusimetric methods. There was satisfactory agreement between the two methods. Hence, diffusimetry, a simple readily performed method, may be considered as an orientative test of the greatest utility, available for any of the lesser clinical laboratories.