Modification of the atherogenic risk factor Lp (a) by supplementary fish oil administration in patients with moderate physical training
Herrmann, W.; Biermann, J.; Lindhofer, H.G.; Kostner, G.
Medizinische Klinik 84(9): 429-433
1989
ISSN/ISBN: 0723-5003 PMID: 2530431 Document Number: 337866
Influence of supplementary fish oil diet in patients with moderate physical training on the atherogenic risk factor Lp(a) 32 male patients (mean age 54.0 +/- 5.8 years) were treated with supplementary fish oil intake (8 ml/d) and daily moderate swim training (20 to 30 min) for four weeks. In 22 of the 32 patients lipoprotein Lp(a) was reduced significantly by 25.0%, apolipoprotein (apo) B by 11.4%, apo A I by 7.8%, triglycerides by 38.3%, and cholesterol by 12.3%. Possibly caused by too low dosed fish oil no drop of Lp(a) was seen in ten patients. Caloric reduced diet (5000 kJ/d) did not effect additional decrease of the Lp(a) level. A control group of 22 male patients (52.9 +/- 5.7 control group of 22 male patients (52.9 +/- 5.7 years) trained in the same way received a supplementary peanut oil diet (8 ml/d). There was no influence on Lp(a) by n-6 PUFA but cholesterol and triglycerides dropped significantly.