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Changes in the rosette-forming capacity of peripheral blood lymphocytes in patients with ischemic heart disease after administration of atherogenic lipoproteins

Vasil'chenko, E.M.; Beĭko, V.A.; Tymchishin, P.N.; Karpov, R.S.

Kardiologiia 29(2): 53-56

1989

ISSN/ISBN: 0022-9040
PMID: 2786106
Document Number: 339121
Low-density lipoproteins, isolated from the serum of patients with hypercholesterolemia (dislipoproteinemia, type IIa), increased significantly the number of active and recovered rosette-forming cells (RFC) at incubation with lymphocytes of coronary patients. The use of lipoproteins, belonging to all atherogenic classes, did not essentially alter lymphocyte ability to form total E-RFC. Purified apolipoprotein B reduced lymphocyte capacity for active rosette formation.

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