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Effect of a 30-day period of hypokinesia on various physiologic and biochemical indicators during maximal physical load

Buzulina, V.P.; Machinskii, G.V.; Nosova, E.A.; Stepantsov, V.I.

Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 23(2): 40-44

1989

ISSN/ISBN: 0321-5040
PMID: 2716268
Document Number: 337522
Exercise tolerance of test subjects who remained bed rested (Group A) and who exercised while being supine (Group B) was measured before and after 30-day head-down tilt (-8 degrees). Special attention was given to the parameters that characterize energy supply of working muscles. The data obtained after 30-day bed rest did not reveal any changes in the Group B subjects and showed the following changes in the Group A subjects: maximum oxygen consumption decreased by 10.1% (p less than 0.05), the time within which the anaerobic metabolism threshold was attained decreased by 17.2% (p less than 0.05), and lactate concentration at the workload end decreased by 24.7%, while the pyruvate concentration and the lactate/pyruvate ratio remained unchanged. The results indicate that prolonged aerobic workload after 30-day bed rest seems to be limited by functional changes in oxygen transport rather than by the factors associated with changes in energy supply of working muscles.

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