The effect of thrombocytapheresis on hematologic, biochemical and immunologic indicators
Nepomucká, J.; Vítek, A.; Sejkorová, J.; Motejlová, A.; Horejsí, J.
Vnitrni Lekarstvi 37(4): 359-365
1991
ISSN/ISBN: 0042-773X PMID: 2053306 Document Number: 379961
The authors investigated in 33 separate donors the influence of thrombocytapheresis on haematological, biochemical and some immunological parameters. The paired t-test revealed a statistically significant increase of values of total proteins, aspartate aminotransferase, immunoglobulin A, alpha 1 antitrypsin, transferrin and the C4 component of complement seven days after apheresis and a significant increase of thrombocyte, total protein, alkaline phosphatase, immunoglobulin A, orosomucoid, and transferrin levels two weeks after apheresis. A significant decrease of haemoglobin values was recorded 7 and 14 days after apheresis. As the revealed changes of the investigated parameters are within the physiological range of the healthy adult population, the authors conclude that thrombocytapheresis does not have an adverse effect on the health status of donors.