Coronary artery bypass grafting in a patient with Sjögren's syndrome and other autoimmune diseases
Kurisu, K.; Matsui, K.; Nakashima, A.; Kohno, H.; Kajiyama, K.; Fukuyama, T.
Nihon Kyobu Geka Gakkai 37(10): 2207-2211
1989
ISSN/ISBN: 0369-4739 PMID: 2584785 Document Number: 337291
Coronary arterial involvement in collagen disease is a very rare complication. Particularly in Sjögren's syndrome is there no report of coronary artery bypass grafting (CABG). We report a 68-year-old woman with various autoimmune diseases who underwent successful CABG for unstable angina pectoris. She had a history of Sjögren's syndrome, hypothyroidism, thrombocytopenia and lupoid hepatitis, and had been on the regimens of prednisolone and levothyroxine sodium during the last 4 years. Two months prior to admission when the doses of these drugs were increased, she began to complain of angina on mild exertion and occasionally even at rest. Selective coronary angiograms revealed 75% stenosis at Seg. 2 and 99% stenosis at Seg. 6. Based on these findings and severity of the angina, saphenous vein CABG to the posterior descending and the left anterior descending branches was performed. Despite the associated autoimmune diseases, the patient's postoperative course was uneventful and she is now doing well with no attack of angina, 12 months following the operation.