Clinical significance of cyclic nucleotide metabolism and calcium level in children with arrhythmia
Ternova, T.I.; Bakanov, M.I.; Bershova, T.V.; Mikhaĭlova, I.L.; Danilova, N.V.
Kardiologiia 29(1): 13-17
1989
ISSN/ISBN: 0022-9040 PMID: 2733307 Document Number: 336135
The cyclic nucleotides (CN) system and Ca2+ content were examined in children with various heart rhythm disorders (HRD). Marked changes were demonstrated which correlated to clinical manifestations of the arrhythmias: their type, phase, duration and favorable changes in their course. Antiarrhythmic therapy was associated with a normalization of the altered levels of cyclase components and Ca2+. The results suggest that intracellular metabolism regulation may be disrupted in HRD cases and play an important role in the development of arrhythmias.