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Effects of emotional-pain stress on induction of P-450 cytochrome in the rat liver

Ugolev, A.T.; Dudchenko, A.M.; Belousova, V.V.; Luk'ianova, L.D.

Biulleten' Eksperimental'noi Biologii i Meditsiny 108(7): 48-50

1989

ISSN/ISBN: 0365-9615
PMID: 2478209
Document Number: 334299
Stress effect on cytochrome P-450 content in rat liver has been studied. There is evidence to the effect that stress factors of different origin cause the decline in cytochrome P-450 content both in the control group and in the conditions of induction. The data obtained enable us to suppose that stress causes intensification of cytochrome P-540 degradation process, the induction efficiency being steady.

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