Effect of antitubercular preparations on the function of the ciliary epithelium of the respiratory tract mucosa
Syrovatka, I.A.
Problemy Tuberkuleza 2: 50-51
1989
ISSN/ISBN: 0032-9533 PMID: 2784856 Document Number: 333171
The effect of various concentrations of streptomycin, isoniazid, rifampicin and ethambutol on the function of the siliated epithelium of the frog oral mucosa was studied (110 experiments with 50 frogs). The level of inhibition of the siliated epithelium function depended on the properties of the drugs and their concentration in solution. More pronounced inhibition was induced by 15 per cent ethambutol solution and 10 per cent isoniazid solution. The least inhibition of the siliated epithelium function was observed with the use of 6.25 per cent streptomycin solution, 5 per cent isoniazid solution, 7.5 per cent ethambutol solution and 3.75 per cent rifampicin solution.