Diphosphonates. Current trends and therapeutic prospects
Raviolo, P.; Galvagno, G.; Biarese, V.; Lovisetto, P.
La Clinica Terapeutica 129(1): 31-41
1989
ISSN/ISBN: 0009-9074 PMID: 2525450 Document Number: 332210
Diphosphonates are compounds characterized by a P-C-P bond. They are thus analogs of pyrophosphate and can be useful for treating several bone diseases. The authors synthetically review the mechanism of action of these drugs and their most important clinical applications. The authors finally mention the interesting therapeutic possibilities deriving from the development of new members of this class.