Effect of the combined action of cadmium and ethyl alcohol or cadmium and acetaldehyde on the genesis of sister chromatid exchange in lymphocytes of human blood in vitro
Bassendowska-Karska, E.; Zawadzka-Kos, M.
Roczniki Panstwowego Zakladu Higieny 40(1): 53-57
1989
ISSN/ISBN: 0035-7715 PMID: 2602856 Document Number: 331639
The frequency of exchange of sister chromatids was studied in vitro in peripheral blood lymphocytes of three healthy donors. Mixtures: 3.1 X 10(-3) mM of cadmium sulphate and 43.4 mM of ethanol or 6.2 X 10(-3) mM of cadmium sulphate and 43.4 mM of ethanol or 6.2 X 10(-3) mM of cadmium sulphate and 43.4 mM of ethanol increased significantly the number of these exchanges in only one donor. Mixtures of 0.18 mM of acetaldehyde with cadmium sulphate in three concentrations: 1.6 X 10(-3) mM, 3.2 X 10(-3) mM and 6.2 X 10(-3) mM increased significantly the frequency of exchanges in all donors.