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The mechanism of RNA synthesis in the influenza virus

Varich, N.L.

Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 8: 3-13

1989

ISSN/ISBN: 0208-0613
PMID: 2682224
Document Number: 331527
The influenza virus RNA replication and transcription have been extensively studied both in infected cell and in vitro systems. The review presents the analysis of experimental data on the molecular mechanisms for influenza virus RNA replication and transcription as well as on the regulation of the synthesis of three kinds of virus-specific RNAs (vRNA, cRNA and mRNA) and their interrelationships. A hypothetical pattern of regulation is presented, providing an explanation for change in the rate of synthesis of RNA segments and their transcripts in the course of the replication cycle.

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