Serum protein polymorphisms (HP; TF-, GC- and PI-subtypes) in Sardinia
Walter, H.; Dannewitz, A.; Eberhardt, D.; Trautmann, M.; Pacaci, M.; Rickards, O.; De Stefano, G.F.; Biondi, G.
Gene Geography a Computerized Bulletin on Human Gene Frequencies 3(2-3): 165-171
1989
ISSN/ISBN: 0394-249X PMID: 2518844 Document Number: 330696
Haptoglobin (HP), transferrin (TF), group-specific component (GC) and alpha-1-antitrypsin (PI) polymorphisms have been studied in Sardinia and the following gene frequencies have been found: HP*1 = 0.389, TF*C1 = 0.754, TF*C2 = 0.213, TF*C3 = 0.032, GC*1F = 0.193, GC*1S = 0.546, GC*2 = 0.260, PI*M1 = 0.607, PI*M2 = 0.221, PI*M3 = 0.126, PI*S = 0.040 and PI*Z = 0.006. These findings confirm the genetic uniqueness of Sardinians compared to the other Italian populations.