Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of essential phospholipids (EPL) on the course of chronic poisoning with organic solvents in rats

Put, A.; Samochowiec, L.; Wyczarska-Szok, K.; Wójcicki, J.

Medycyna Pracy 40(4): 220-227

1989

ISSN/ISBN: 0465-5893
PMID: 2628692
Document Number: 329421
Male Wistar rats were exposed in toxicological camera to the mixture of organic solvents. Composition and concentrations of the mixture were similar to the conditions in the production hall. The influence of essential phospholipids (EPL) on changes in the liver caused by the organic solvents were studied. Animals were exposed for 6 months. Histochemical and histological evaluation was performed after 2 and 6 months. In the liver of intoxicated animals marked vacuolar degeneration and diminution of glycogen contents were observed. Simultaneously, the protective effect of EPL was noted. It was expressed by distinctly decreased vacuolar degeneration, probably corresponding to neutral fat in hepatocytes as well as by normalization of glycogen contents.

Document emailed within 1 workday
Secure & encrypted payments

Ceglecka, M. 1992: Effect of pollen extract (Cernitin) on the course of poisoning with organic solvents (biochemical analysis) Annales Academiae Medicae Stetinensis 38: 79-95
Rózewicka, L.; Kadłubowska, D. 1978: Effect of essential phospholipids on the lipid content in the liver and myocardium of rats fed a high-fat diet Folia Biologica 26(4): 249-255
Laass, W.; Bräter, E.; Tietze, G. 1977: The suitability of Carbo medicinalis for the treatment of oral poisoning with organic solvents Die Pharmazie 32(8-9): 542
Bazydło-Golińska, G. 1993: The effect of organic solvents on the inner ear Medycyna Pracy 44(1): 69-78
Müting, D.; Dohn, P.; Reikowski, J. 1972: Effect of high-dose, intravenous and oral administration of essential phospholipids on protein and lipid metabolism as well as enzyme activities in patients with chronic liver disease Verhandlungen der Deutschen Gesellschaft für Innere Medizin 78: 1389-1392
Knezević, M.; Sulović, V. 1995: Effect of organic solvents on gynaecological diseases Srpski Arhiv Za Celokupno Lekarstvo 123(5-6): 123-125
Spisni, R.; Valentini, P.; Nervi, M.; Ciampalini, G.; Lijoi, C.; Luciani, L. 1988: Pirenzepine in the treatment of chronic gastritis in patients exposed to organic solvents Minerva Dietologica E Gastroenterologica 34(4): 265-268
Langauer-Lewowicka, H.; Witecki, K.; Braszczyńska, Z.; Wocka-Marek, T.; Byczkowska, Z. 1983: Effect of organic solvents on the central nervous system Neurologia i Neurochirurgia Polska 17(4): 465-470
Moszczyński, P.; Lisiewicz, J. 1983: Effect of organic solvents containing benzene and its homologues on the hematopoietic system Przeglad Lekarski 40(4): 391-396
Sińczuk-Walczak, H. 1992: Current state of studies on the effect of organic solvents on the nervous system Medycyna Pracy 43(6): 543-548
Satoh, K.; Sakagami, H.; Terasaka, H.; Ida, Y.; Fujisawa, S. 2000: Interaction between hydroquinone and ascorbic acid derivatives: quenching effect of organic solvents Anticancer Research 20(3a): 1577-1581
Moszczyński, P.; Słowiński, S.; Moszczyński, P. 1991: Synergistic effect of organic solvents and tobacco smoke on the indicators of humoral immunity in humans Gigiena Truda i Professional'nye Zabolevaniya (3): 34-36
Tikhonova, G.I.; Lebedeva, N.V.; Fedorova, B.V. 1997: The effect of organic solvents on the child-bearing function of women painters (an epidemiological hygiene study Meditsina Truda i Promyshlennaia Ekologiia 3: 20-24
Rauen, H.M.; Schriewer, H.; Gebauer, B.; Abu Tair, M. 1973: The effect of essential phospholipids following acute experimental CCl4 liver injury Arzneimittel-Forschung 23(9): 1332-1334
Cherniavs'kyĭ, P.V.; Datsenko, Z.M.; Moiseieva, L.H.; Kanivets', N.V.; Kozulina, O.P.; Boroda, A.M.; Abakumova, O.S. 2006: Regulation of intracellular lipid metabolism by the preparation of omega-3 phospholipids from marine organisms in deficiency of essential fatty acids in rats Ukrains'kyi Biokhimichnyi Zhurnal 78(5): 101-113
Kristensen, P.; Tvedt, B.; Levy, F. 1989: Late sequelae after occupational exposure to organic solvents. Exposure assessment in diagnosing chronic toxic encephalopathy Tidsskrift for den Norske Laegeforening: Tidsskrift for Praktisk Medicin Ny Raekke 109(19-21): 2012-2016
Jensen, P.B.; Nielsen, P.; Nielsen, N.O.; Olivarius, B.D.; Hansen, J.H. 1984: Chronic toxic encephalopathy following occupational exposure to organic solvents. the course after cessation of exposure illustrated by a neurophysiological follow-up study Ugeskrift for Laeger 146(18): 1387-1390
Turecký, L.; Kupcová, V.; Szántová, M.; Laktis, K.; Uhlíková, E. 1996: Plasma proteins in patients with liver steatosis and the effect of treatment of essential phospholipids Bratislavske Lekarske Listy 97(10): 625-628
Stiehl, A.; Czygan, P.; Götz, R.; Raedsch, R.; Fröhling, W. 1978: The effect of essential phospholipids on the composition of the bile and on intestinal activity during treatment with chenodeoxycholic acid Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1978(84): 1105-1106
Gurevich, V.S.; Eliseev, V.V.; Shatilina, L.V.; Krylova, I.V. 1992: Effect of essential phospholipids on intensity of lipid peroxidation in the myocardium in experimental post-hypoxic reoxygenation Voprosy Meditsinskoi Khimii 38(2): 55-57